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Friday, July 24, 2020 | History

2 edition of Protein kinase CK2 found in the catalog.

Protein kinase CK2

Protein kinase CK2

from structure to regulation

  • 263 Want to read
  • 10 Currently reading

Published by Kluwer Academic Publishers in Dordrecht, Boston .
Written in English

    Subjects:
  • Protein kinase CK2.,
  • Protein kinase CK2 -- Pathophysiology.

  • Edition Notes

    Includes bibliographical references and index.

    Statementedited by Khalil Ahmed, Jorge E. Allende, Olaf-Georg Issinger.
    ContributionsAhmed, Khalil, 1934-, Allende, Jorge E., Dr., Issinger, O. G.
    Classifications
    LC ClassificationsQP606.P76 P7355 2001
    The Physical Object
    Pagination187 p. :
    Number of Pages187
    ID Numbers
    Open LibraryOL20644532M
    ISBN 100792376668
    LC Control Number2001050790

    These characteristics make CK2 a housekeeping kinase that can modify protein functions and protein turnover in a dynamic way. In the context of ABA signaling, CK2 is already known to promote SnRK2 degradation through the 26S proteasome and inactivation through the interaction with PP2C, and has been connected with ABAR by: Casein kinase II (CK2) is a Ser/Thr protein kinase of broad substrate specificity that is widely distributed among eukaryotic organisms. Both the structure and the function of the enzyme are highly conserved. The physiological role of CK2 is poorly understood, but the enzyme is essential for viability in Saccharomyces cerevisiae(S. cerevisiae).

    Protein kinase CK2 (formerly casein kinase II or 2) is known to play a critical role in the control of cell growth and cell death and is thus intimately involved in the development of cancer. More specifically, CK2 has been found to be elevated in all cancers examined. The protein kinase CK2 is a highly conserved serine/threonine kinase distributed ubiquitously in eukaryotic urally, CK2 can exist in a tetramer comprising two catalytic subunits, CK2α and CK2α′, associated with two regulatory subunits, termed by: 6.

      Human protein kinase CK2 represents a novel therapeutic target for neoplastic diseases. Inhibitors are in need to explore the druggability and the therapeutic options of this enzyme. A bottleneck in the search for new inhibitors is the availability of the target for by: Casein Kinase II. Cite this entry as: () Protein Kinase CK2. In: Choi S. (eds) Encyclopedia of Signaling Molecules.


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Protein kinase CK2 Download PDF EPUB FB2

With contributions from the world’s leading experts in the field, Protein Kinase CK2 will serve as an invaluable guide to the expanding and vibrant body of research being performed on this enzyme. This will be an essential volume for anyone working in the fields of biochemistry, protein science, signal transduction, metabolic regulation, and cancer biology and by: With contributions from the world’s leading experts in the field, Protein Kinase CK2 will serve as an invaluable guide to the expanding and vibrant body of research being performed on this enzyme.

This will be an essential volume for anyone working in the fields of biochemistry, protein science, signal transduction, metabolic regulation, and cancer biology and therapeutics. Protein Kinase CK2 Cellular Function in Normal and Disease States (Advances in Biochemistry in Health and Disease): Medicine & Health Science Books @ Skip to main content Try Prime.

With contributions from the world’s leading experts in the field, Protein Kinase CK2 will serve as an invaluable guide to the expanding and vibrant body of research being performed on this enzyme. This will be an essential volume for anyone working in the fields of biochemistry, protein science, signal transduction, metabolic regulation, and cancer biology and : : Protein Kinase CK2 - From Structure to Regulation (Developments in Molecular and Cellular Biochemistry) (): Ahmed, Khalil: Books.

CK2 is a protein serine/threonine kinase which is a highly conserved and ubiquitous protein kinase. It Protein kinase CK2 book localized in the cytoplasmic and nuclear compartments, which accords with its multiple functional activities in the cell. Pertinent to this is also the recognition that a large number of.

Protein Kinase CK2 Cellular Function in Normal and Disease States (Advances in Biochemistry in Health and Disease Book 12) - Kindle edition by Ahmed, Khalil, Issinger, Olaf-Georg, Szyszka, Ryszard. Download it once and read it on your Kindle device, PC, phones or tablets. Use features like bookmarks, note taking and highlighting while reading Protein Kinase CK2 Cellular Function in Normal and Price: $ About this book Protein kinase CK2 (formerly casein kinase II or 2) is known to play a critical role in the control of cell growth and cell death and is thus intimately involved in the development of cancer.

More specifically, CK2 has been found to be elevated in all cancers examined. Protein Kinase CK2 - From Structure to Regulation by Khalil Ahmed,available at Book Depository with free delivery worldwide. The Interactome of Protein Kinase CK2. Mathias Montenarh.

Medical Biochemistry and Molecular Biology, University of the Saarland, Homburg, Germany. Book Editor(s): Lorenzo A. Pinna. University of Padua, Department of Biomedical Sciences, Padua, by:   The protein kinase CK2 is a Ser/Thr kinase that is expressed ubiquitously and highly conserved (17 – 19).

CK2 consists of two catalytic (α) and two regulatory (β) subunits, which form an α 2 β 2 heteromeric by: Protein Kinase CK2 is logically divided into three sections. The first section reviews key molecular and structural aspects of the enzyme.

The second section looks at functional aspects of CK2 and the diverse roles it plays in cellular development, function, and cturer: Wiley-Blackwell.

The involvement of protein kinase CK2 in sustaining cancer cell survival could have implications also in the resistance to conventional and unconventional therapies.

Moreover, CK2 role in blood tumors is rapidly emerging and this kinase has been recognized as a potential therapeutic by: Protein Kinase CK2 plays equally important functions in development and intracellular activities, and has a global impact on cell growth and proliferation.

Protein kinase CK2 (CK2) is a ubiquitous serine/threonine protein kinase for hundreds of endogenous substrates.

CK2 has been considered to be involved in many diseases, including cancers. Herein we report the discovery of a novel ATP-competitive CK2 inhibitor. Virtual screening of a compound library led to the identification of a hit 2-phenyl-1,3,4-thiadiazole by: Protein kinase CK2 is a ubiquitous protein kinase responsible for the phosphorylation of Ser and Thr residues specified by acidic side chains in many proteins, including several key enzymes, growth factor receptors, transcription factors and cytoskeletal by:   CK2 is a ubiquitously expressed protein kinase and regulates a wide variety of biological processes, including cell growth and survival, gene expression, and actin cytoskeleton organization (Meggio and Pinna, ).Cited by:   With contributions from the world’s leading experts in the field, Protein Kinase CK2 will serve as an invaluable guide to the expanding and vibrant body of research being performed on this enzyme.

This will be an essential volume for anyone working in the fields of biochemistry, protein science, signal transduction, metabolic regulation, and cancer biology and : Wiley.

Free 2-day shipping. Buy Protein Kinase Ck2 Hardcover at nd: Pinna, Lorenzo A. CK2 is a protein serine/threonine kinase which is a highly conserved and ubiquitous protein kinase. Additionally, the shuttling of the kinase to various compartments in.

CK2 is a protein serine/threonine kinase which is a highly conserved and ubiquitous protein kinase. It is localized in the cytoplasmic and nuclear compartments, which accords with its multiple functional activities in the cell.Protein kinase CK2.

[Lorenzo A Pinna;] Print book: EnglishView all A Major Molecular Chaperone Co-Chaperones That Regulate Hsp90 Function Hsp90 and Signaling Protein Kinases Phosphorylation and the Regulation of Hsp90 by CK2 Phosphorylation of Cdc37 by CK2 A Crucial Role of CK2-Dependent Phosphorylation in the.Protein Kinase CK2 will deal with structural aspects underlying the constitutive activity of CK2, its specific susceptibility to pharmacological inhibition and its extraordinary pleiotropy.

In the second part the fundamental role of CK2 in a w.\/span>\"@ en\/a> ; \u00A0\u00A0\u00A0\n schema:description\/a> \" pt. 1. Molecular and structural.